How The Binding of Isaac Was Made and Designed to Fail

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Isaac, but Every 5 Minutes You Make it WEIRD

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I made a BIG Mistake :(

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Isaac Makes Yerba Mate Tea

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Isaac Delusion — Make It (feat. Silly Boy Blue)

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Isaac School District teachers go unpaid, may not go to work Wednesday

(3:44)

THE HARDEST CHARACTER in BINDING OF ISAAC makes me question reality

(19:39)

Edmund McMillen Breaks Down His Game Design History (Meat Boy, Isaac \u0026 More) | Noclip

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Isaac Makes his New Favorite Drink

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Trying INDIAN FOOD for the FIRST TIME!

(9:15)

Non-Isaac Players Make ALL of the Decisions

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The insanity of The Binding of Isaac

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SUKUNA BUILD in isaac

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Edit Like Isaac to Break YouTube with 1 Video

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I Made The Binding Of Isaac but it’s 3D

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The Binding of Isaac RUINED Video Games For Me...

(12:40)

Which Tainted Isaac Characters Could I beat in a Fight?

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